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When to Reassess If injection-site reactions worsen instead of improving over the first week, if fatigue persists past the loading phase, or if any unusual symptom appears, pause the protocol and consult a qualified clinician

We advise against use in patients with active cancer, cardiovascular disease, autoimmune disorders, liver or kidney disease, clotting issues, pregnancy or breastfeeding, or those under age 20

When administered, it rapidly restores vitamin B12 levels, particularly benefiting those with disorders of red blood cell production and nervous system anomalies due to deficiency

Obese individuals may require doses at the higher end of the range, though this should be done under medical supervision

B cells promote tumor progression via STAT3 regulated-angiogenesis

Int J Biol Macromol (2024) 283:137591