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Glutamine-addicted cells exhibit a decreased survival, or even undergo apoptotic cell death, associated with an increased in DNA damage, an overproduction of ROS or a decreased reduced/oxidized glutathione (GSH/GSSG) ratio

J Physiol (Paris) 1993

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RNA-seq analysis revealed that DEGs between 0 mg/kg and 2 mg/kg anwuligan-treated mice were significantly enriched in several key pathways, including metabolic pathways, protein digestion and absorption, retinol metabolism, MAPK signaling pathway, PI3KAkt signaling pathway, Wnt signaling pathway, PPAR signaling pathway, BMP signaling pathway, and TGF-beta signaling pathway

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But as Joe Beer explains, new evidence suggests that we may have been too quick to dismiss its ergogenic properties