Medicare currently limits its coverage of GLP-1s to individuals with Type 2 diabetes or certain heart conditions, excluding prescriptions aimed solely at obesity
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Knockdown of IL-10 receptor- or pharmacological inhibition of STAT3 activation abolished exenatide-induced -endorphin expression and its antiallodynic effects [63]
By reducing androgens and improving insulin resistance, GLP-1 agonists support regular ovulation, making them a promising option for addressing PCOS-related infertility
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