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Chronic symptoms, such as abdominal pain potentially linked to eosinophilic esophagitis (EoE), are a common reason for discontinuation of therapy [91]

If the reaction happens within minutes of taking the supplement, it is more likely an acute allergic response

No antibody formation When the immune system recognizes a foreign protein and produces antibodies against it, this can reduce the compound effectiveness over time and potentially cause allergic reactions

Nassan FL, Chavarro JE, Tanrikut C

And even worse than that, all of these other minerals play a central role in plants and plants have homeostasis controlling how much they take up from the soil