Shaik, I.H
In November 2023, the FDA added BPC-157 to its list of substances that cannot be used in compounding under the Federal Food, Drug, and Cosmetic Act, citing insufficient safety data for human use 3
The Trump administration announced in April 2025 that Medicare would not cover GLP-1 drugs for weight loss, reversing a Biden-era decision
Further, unlike GLP-1, GIP increases triglyceride storage in white adipose tissue, does not delay gastric emptying, and may impact bone remodeling--functions that were thought to limit GIPs utility in T2D and weight loss
According to FDA-approved prescribing information for semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound), food intake does not significantly affect the absorption or efficacy of these subcutaneous injections
[5] Unlike the more common papillary or follicular thyroid cancers, MTC can occur in hereditary forms associated with MEN 2, an autosomal dominant syndrome caused by mutations in the RET proto-oncogene
