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As a stimulant and diuretic, caffeine can contribute to dehydration if you arent consuming plenty of fluids (water, in particular) at the same time

doi: 10.1001/jamacardio.2018.0022 218 HowardBVVan HornLHsiaJMansonJEStefanickMLWassertheil-SmollerSet al

Very high doses may potentially lower zinc levels or interact with certain medications, including chemotherapy and immunosuppressants

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Abd-Elhakim YM, Mohamed WA, Bohi KME, Ali HA, Mahmoud FA, Saber TMJG: Prevention of melamine-induced hepatorenal impairment by an ethanolic extract of Moringa oleifera: Changes in KIM-1, TIMP-1, oxidative stress, apoptosis, and inflammation-related genes

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