Age and sex but not ATP7B genotype effectively influence the clinical phenotype of Wilson disease
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3.2.2 Relationship between lipid peroxidation and ferroptosis Lipid peroxidation manifests as a continuous process of free radical production and reactiona chain reaction that severely compromises cell membrane integrity, ultimately leading to organelle and/or cell membrane rupture (42)
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Additionally, the total necrotic area was significantly decreased in the HCD + ALC group (Figures 5F,G)