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23 , 99112 Two RCTs 99 , 110 and 5 meta-analyses 23 , 100102 , 109 reported benefits of vitamin B 12 supplementation in methylcobalamin (0.51 mg orally or local injection for 2 weeks to 1 year) and cyanocobalamin (2000 mg orally or 11000 mg via intramuscular route for 90 days and 4 months) forms

Although PPV was considered an attractive strategy for PCa, and even after successful phase II trials, the phase III trial of 310 patients with mCRPC receiving docetaxel found no survival advantage over PBO (HR 1.04