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For instance, creatine should not be used by individuals with pre-existing renal disease or those with a potential risk for renal dysfunction (diabetes, hypertension, reduced glomerular filtration rate) [11]

Turino GM, Ma S, Lin YY, Cantor JO

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5.3.3 Bile acids High-fat diet (HFD) reshapes microbiota-dependent bile acid metabolism and promotes the accumulation of secondary bile acids such as deoxycholic acid (DCA) (152)

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In one study, the antioxidant capacity of individuals with IBD was found to be significantly lower than those without the disease (Kruidenier 2003)