In these situations, documented failed trials on the covered medication may eventually justify approval for the preferred option
Patients should seek immediate medical attention for and discontinue semaglutide if they experience: Severe, persistent abdominal pain (possible pancreatitis) Signs of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness) Symptoms of gallbladder disease (right upper quadrant pain, especially after meals) Severe hypoglycemia (when combined with insulin or sulfonylureas) Signs of kidney problems (decreased urination, swelling, fatigue) Suicidal thoughts or behaviors (particularly with Wegovy) Vision changes (especially in patients with diabetes and pre-existing retinopathy) Regular follow-up with healthcare providers is essential to monitor treatment response, adjust dosing, manage side effects, and assess cardiovascular risk factors including blood pressure, glucose control, and lipid profiles
Grander C, Adolph TE, Wieser V, Lowe P, Wrzosek L, Gyongyosi B, et al
The Centers for Disease Control and Prevention (CDC) estimates that more than 40% of US adults have obesity and 11% have diabetes (National Center for Health Statistics, 2023
Comparisons with Other Treatments When comparing sertraline to other treatments for depression and anxiety, it is important to consider both effectiveness and side effects
(This connection has only been established in animal studies.) Mood changes: Watch for any new or worsening mental health symptoms, such as depression
