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Stable isotope tracing For isotope tracing experiments, day 10 SCD erythroblasts were cultured with the treatment of hemin, DMF, or both for 40 h

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Rev Neurosci

J Exp Clin Cancer Res Ferroptosis inducers enhanced cuproptosis induced by copper ionophores in primary liver cancer

Briefly, Mercury(II) ions present in the environment cross the microorganisms cellular membrane and are scavenged by MerA, a homo-dimeric enzyme which sandwiches the Hg 2+ between a pair of catalytically essential cysteine thiol groups, to make a protein-embedded mercury(II)-bis-thiolate

These results are not unprecedentedour lab has shown that some RNA viruses target host mRNAs encoding isoforms of thioredoxin reductase via RNA:RNA antisense interactions, which, like proteolysis, would likely also result in host selenoprotein knockdown, but by a different mechanism (22, 33)