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Similarly, it is now possible to perform spatially-differentiated multi-omic tissue profiling, such that the content of DNA, production of transcripts, and expression of proteins thus discovered can be differentiated according to precise cellular, or even sub-cellular, origin

This could mean multiple physical changes that happen in depression (likely) or it could mean that some of the research is wrong and/or that Im not understanding it correctly (also likely)

Moreover, markers of senescence, such as SA--gal and SASP, have been detected in patients treated with IR [91]

GLP-1RAs alleviate vascular aging under chronic stress via increasing adiponectin (APN) levels and inhibiting aortic MMP-9 and MMP-2 expression in ApoE -/- mice [96, 149]

Directed research on GHK

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