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The pharmacokinetics of tirzepatide after a single 5 mg dose was evaluated in patients with different degrees of hepatic impairment (mild, moderate, severe) compared with subjects with normal hepatic function [see Use in Specific Populations (8.7)]

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FDA approval would provide standardized, quality-controlled formulations with proper dosing guidance

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Prior evidence has indicated that GGCT plays a critical role in maintaining redox balance and prolonging lifespan in red blood cells via the regulation of GSH metabolism, providing a key clue for exploring the crosstalk between Gln and GGCT in cancer [31]

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Interactions of urate transporter URAT1 in human kidney with uricosuric drugs

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