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Ozempic should be used with caution in patients with a history of pancreatitis, and following a confirmed episode of pancreatitis whilst on semaglutide, the medication must not be restarted

This dissociation suggests that tolerability may depend not solely on total weight loss or dose intensity, but on mechanistic distinctions between dual incretin agonism and GLP-1only therapy

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Understanding tirzepatide's actual effects on blood pressure helps patients and clinicians optimize treatment safety and manage concurrent antihypertensive medications appropriately during therapy

Clinical trials have shown promising results for both medications, but individual responses may vary

Plateau while taking GLP medication