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Endocrinology 138, 44454455

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Mechanistically, this may relate to GHK-Cu's ability to upregulate matrix metalloproteinases (MMP-1, MMP-2), enzymes that can fragment collagen if their activity exceeds the body's ability to rebuild

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10.3390/ijms18081638 116 YangT.LiangZ.WenC.JiangX.WangL

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2017 Jul;55(6):569-572

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The Phase 2b trial used subcutaneous injection, not oral formulation

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