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Recent data indicate the presence of neuroinflammation and neurotoxic consequences in the CNS of patients with MDD [1]

It binds directly to GHRH receptors on somatotroph cells in the anterior pituitary, enhancing both the amplitude and duration of GH secretion

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For patient 2, informed consent was obtained under the approval of the Ethics Committee of Universittsklinikum Dsseldorf (reference number 37162907)

Semaglutide is currently available under four brand names, each of which the US Food and Drug Administration (FDA) has approved for different conditions: Wegovy pill, a daily oral tablet, is approved to reduce body weight in adults with obesity or overweight and lower cardiovascular risk in adults with heart disease and obesity or overweight