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However, a clinical evaluation is required before treatment to confirm candidacy and design the appropriate protocol
10.1016/j.aca.2005.02.033 Anal Chim Acta
J Interferon Cytokine Res
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Several small molecules identified in a drug screening appear to converge on metal ion chelation and/or inhibition of NF-B and Akt/GSK3 pro-survival signaling pathways To get further insights into the molecular mechanisms involved in the regulation of CBS activity, we screened a set of 2,932 small molecules from the National Cancer Institute, consisting in diverse chemical scaffolds, including natural products and approved oncology drugs
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