The following situations require a clinician conversation or same-day care: Contact within 48 hours if: vomiting prevents you from keeping down water for more than eight hours, diarrhea produces signs of dehydration, constipation has not responded to an osmotic laxative after five days, or symptoms worsen at a stable dose after week 12
10.1016/j.scienta.2015.11.047 65 HarrachB
Clin Ther, 2020, Vol 42(1) pp 94105
During medication shortages, compounded versions of drugs, like semaglutide, can be prescribed when FDA-approved options aren't available
Someone with severe insulin resistance may see blood sugar improvements within days but slower weight loss initially
Arch Biochem Biophys 2008;478:136142