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Others struggle through the entire four-month ramp-up period

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Preserving lean tissue helps maintain metabolic rate throughout and after weight loss

This weight gain is primarily due to fluid buildup and is temporary

Beyond blood pressure control, clonidine has diverse off-label applications, including management of attention-deficit/hyperactivity disorder (ADHD), Tourette syndromeassociated tics, and autonomic hyperactivity during opioid, alcohol, and nicotine withdrawal

This diminishing return is crucial information for anyone building a protocol, because it suggests that 8mg may represent the optimal balance point for many researchers