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There are a number of settings in which this type of efficacy profile could be useful, including the treatment of hyperglycemic conditions
atropine flush Marked excitement and convulsions may occur with toxic doses (in comparison, scopolamine has greater CNS effects)
The therapeutic efficacy of BM-MSCs can be significantly reduced by blocking the vagus nerve, administering drug inhibitors, or implementing gene knockout to inhibit CAP, and BM-MSC-derived prostaglandin E2 (PGE2) can promote acetylcholine (Ach) synthesis and release
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