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doi:10.1016/0165-0173(91)90007-U

At the cellular level, the lack of insulin leads to the activation of alternative metabolic pathways, in which the liver contributes to the increase in blood sugar by increasing gluconeogenesis and glycogenolysis, while adipose tissue undergoes intense lipolysis and releases large amounts of free fatty acids into the bloodstream

5-Oxoprolinase deficiency Disease name 5-Oxoprolinase deficiency (OMIM 260005) Definition and diagnostic criteria 5-Oxoprolinase deficiency is a very rare autosomal recessive disease characterized by 5-oxoprolinuria and very heterogeneous clinical presentation (renal stone formation, enterocolitis, mental retardation, neonatal hypoglycemia, microcytic anemia and microcephaly)

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10.1111/hel.12898 43 HomanM.OrelR

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