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More research is needed to confirm the long-term safety and effectiveness of semaglutide for alcohol use disorder, while FDA-approved medications remain the primary treatment for managing alcohol cravings and alcohol use disorder

Obesity and weight gain are chronic metabolic conditions

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Hair shedding can occur with some GLP1 medications, especially with rapid weight loss but it is usually temporary, reversible, and manageable, Mirmirani said

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Humoral factors from adipose tissue or adiposity signals, leptin and insulin, are mostly involved in the long-term regulation of food intake and energy metabolism as dictated by energy needs and the amount of energy stores, and can act on both cell types simultaneously to produce satiety through appetite suppression or hunger when the body is in a negative energy state (hungry) [14,15]