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By working on two hormones, it often leads to greater reductions in weight and blood sugar compared to semaglutide

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Who Benefits From Combination Therapy: Provider Decision Framework Combination therapy may be considered in patients with inadequate weight loss response to semaglutide monotherapy alone, documented treatment tolerance after initial side effects, and no contraindications to either agent

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Maintenance Dose: Finding Your Optimal Tirzepatide Level Your maintenance dosethe steady-state tirzepatide amount you sustain long-termoften ranges from 5 mg to 15 mg weekly, though some patients respond exceptionally well at lower doses while others achieve targets at higher levels