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The overall incidence of depression and/or anxiety was lower in GLP1-RA users than non-users (6.80 versus 9.36 per 1,000 person-years), with an aHR of 0.8 (95% CI: 0.670.95) for users, after controlling for demographic factors, comorbidities and medications (Table 2)

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MT-1 (Afamelanotide) induces skin pigmentation and MC1R-mediated photoprotection that physically and biologically shields the skin from the phototoxic light wavelengths activating protoporphyrin

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