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More severe side effects can also happen, but they are less common

The system biology of thiol redox system in Escherichia coli and yeast: differential functions in oxidative stress, iron metabolism and DNA synthesis

Patients with asthma should use glutathione with caution, as there have been reports of bronchial constriction when inhaled glutathione was used

However, anyone can develop dark knuckles

Additionally, long-term use of glutathione may potentially lower zinc levels in some people, so you might consider monitoring your mineral intake if you plan to take it indefinitely

Photos: Courtesy of Brands Elizabeth Siegel is a freelance beauty writer who has covered skin care, plastic surgery, and more for Allure , Oprah Daily , Air Mail , W , Elle , and WWD