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Professional bodies like The Obesity Society and endocrine societies recommend considering medications like Saxenda or Wegovy for patients with BMI 30 (or 27 with comorbidities) who have not achieved weight loss goals with lifestyle changes alone ( [145] ) ( [146] )

What good looks like: Your weight trend is declining at 1 to 2 percent per week, your protein target is being hit most days, and your strength numbers on key lifts are holding steady or improving

The best option depends on several factors, including health history, metabolic health, medication tolerance, side effect response, and long-term weight loss goals

If you are currently on semaglutide and have hit a weight loss plateau , switching to tirzepatide is a well-supported option

Ozempic is more often covered when prescribed for type 2 diabetes, but less commonly for weight loss

However, tirzepatide has a special dual approach that provides unique advantages