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Second, GLP-1 therapies modestly reduce systolic blood pressure

The inhibitory effects of peripheral administration of peptide YY(336) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway

Hold isotretinoin and consult a hepatologist if ALT or AST reaches three times the upper limit of normal [2]

Conclusion While diarrhea can be a challenging side effect of Wegovy, understanding its causes and implementing effective management strategies can help alleviate discomfort

The SURMOUNT-5 trial showed that tirzepatide produced 20.2% body weight reduction compared to 13.7% with semaglutide over 72 weeks, a significant gap that suggests tirzepatide may push past the metabolic ceiling where semaglutide stalls

Weight loss achieved on GLP-1 therapy often improves fertility by reducing insulin resistance and restoring hormonal balance, making pregnancy more likely once you reach a target weight and pause the medication