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[DOI] [PubMed] [Google Scholar] 97.Lee BC, et al

The glucagon receptor activation enhances energy expenditure and promotes fat oxidation, essentially helping the body burn stored fat more efficiently

Tirzepatide: Stands out for its dual agonism (GLP-1 and GIP receptors), resulting in substantial weight loss in addition to glycemic control

Tanemura A, Oiso N, Nakano M, Itoi S, Kawada A, Katayama I (2013) Alopecia areata: infiltration of Th17 cells in the dermis, particularly around hair follicles

Overall, LY2112688 demonstrated robust nonclinical efficacy across three different species, reducing body weight, food intake, and potentially increasing energy expenditure

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