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The results of changes in the diversity and abundance of the human gut microbiota after metformin treatment are not consistent

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The clearest lower-dose maintenance band is 0.5 to 1.0 mg weekly

Mechanistically, T3 suppresses Cyp8b1 expression, resulting in increased the levels of Farnesoid X receptor (FXR)-antagonistic bile acids, thereby potentiating GLP-1 production and insulin secretion by repressing intestinal FXR signalling

Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

The MS proteomics data have been deposited to the ProteomeXchange Consortium through the PRIDE partner repository under dataset identifier PXD045816