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KPV is one of the few peptides with demonstrated oral bioactivity via PepT1 intestinal peptide transporters
For instance, commensal bacteria have been found to produce endocannabinoid-like compounds, such as 2-arachidonoyl glycerol (2-AG), which can activate cannabinoid receptors and modulate gut functions [80]
NMDA receptor channels: Subunit-specific potentiation by reducing agents
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