Endocrinology 141:163168 Pedersen MM, Christensen SE, Christiansen JS, Pedersen EB, Mogensen CE, Orskov H (1990) Acute effects of a somatostatin analogue on kidney function in type 1 diabetic patients
Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process
Smets P, Meyer E, Maddens B, and Daminet S
Cladribine (DB00242) and Gallium nitrate (DB05260) are RRM2-targeted drugs
J Neurochem 2001
Senescent cells are cells that have permanently halted their cell cycle ('replicative arrest') but resist apoptosissometimes called 'zombie cells.' They accumulate with age in multiple tissues and secrete a pro-inflammatory cocktail called the Senescence-Associated Secretory Phenotype (SASP), containing IL-6, IL-8, MMP-3, MMP-9, TNF-, and other factors that damage surrounding healthy tissue