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Multiple supplements have documented 5-AR inhibitory activity: Zinc High-dose zinc inhibits 5-alpha reductase in human skin fibroblasts (Stamatiadis et al., 1988)
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Rajagopal observed that the level of TBARs in the erythrocytes was increased by 50% showing a significant generation of free radicals in the erythrocytes of diabetic patients [19]
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However, higher doses may carry the risk of other adverse effects, including agitation and activation
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