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Nature 380:435439 Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, Shah PK, Willerson JT, Benza RL, Berman DS et al (2003) The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis

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Scenario 3: stable 10 mg weekly with 30 mg vials You have reached your maintenance dose of 10 mg weekly

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A subset of patients on standard NHS maintenance feel their symptoms return well before the next scheduled injection