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Abbreviations used BBB blood brain barrier BBBD blood brain barrier disruption EAAC1 excitatory amino acid carrier type 1 GFAP glial fibrillary acidic protein GSH reduced glutathione GSSG oxidized glutathione HPLC-ECD high performance liquid chromatography with electrochemical detection Iba1 ionized calcium binding adaptor molecule 1 ICAL Immunocal MRI magnetic resonance imaging PBS-T phosphate-buffered saline with 0.1% Triton X-100 PHF paired helical filament PVDF polyvinylidene difluoride SDS-PAGE sodium dodecylsulfate polyacrylamide gel electrophoresis TBI traumatic brain injury Footnotes Conflicts of Interest The authors have received funding from Immunotec Inc