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"We don't know how effective it's going to be

Individual responses to timing vary considerably, and there is no clinical evidence that nighttime administration reduces gastrointestinal side effects compared to other times of day

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What side effects should I be aware of, and how can I manage them

Tell your health care provider if you have any other medical conditions, including if you: Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and other medicines to treat diabetes, including insulin or sulfonylureas