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However, over time, it has gained significant attention for its rapid weight loss effects, which have led to a distinctive facial appearance popularly termed semaglutide face. [1] Semaglutide is associated with various skin-related side effects, including dysesthesia, hyperesthesia, neuralgia, paresthesia, sensitive skin, and a burning sensation upon oral administration

GI side effects are the most common AE class

Abnormal results before starting GLP-1 therapy are not necessarily disqualifying they are informative

Biochemical analyses confirmed increased levels of A40 and A42 at 12 months, and memory deficits were observed by 15 months (Rnnbck et al., 2011

doi:10.21037/tau-20-592

However, it is manageable, and you have several options to help