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doi: 10.1073/pnas.1120210109

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326 Angiotensin II exerts its vasoconstrictive effects primarily through activation of the angiotensin II type 1 receptor

This designation provides more frequent FDA guidance and expedited review

Adverse Reactions/Side Effects Mild transient diarrhea, polycythemia vera, peripheral vascular thrombosis, itching transitory exanthema, feeling of swelling of entire body, anaphylactic shock and death