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"FDA Approves First Treatment to Reduce Risk of Serious Heart Problems Specifically in Adults with Obesity or Overweight"

GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) reduce appetite, slow digestion, and support blood sugar regulation

Both hormones have a very short half-life (the time corresponding to a loss of half of their physiological activity), of only 1-2 minutes, in particular due to their degradation by dipeptidyl peptidase-4 (DPP-4)

Symptoms may appear rapidly, or they may be subtle and easily dismissed this, combined with the fact that patients arent properly warned about these side effects, can result in severe outcomes for GLP-1 users

Understanding the pharmacology helps you anticipate and address nutritional challenges

Theranostics 2022;12:2741-57.ArticlePubMedPMC 88