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When L-cells taste bitter foods, PYY (peptide tyrosine tyrosine) evokes an aversive response to food, increasing release of GLP-1 and shutting down hunger

They are specialized epithelial cells that are organized into interconnected plates called lobules

WJ: Writing original draft, Software

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Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance

Both medications may increase the risk for pancreatitis , or inflammation of the pancreas, though this may be more likely to occur in people with a history of pancreatitis or who have other risk factors