local anesthetic applied Injection Points: Typically include the AC joint capsule and coracoclavicular ligament attachments Solution Used: 15-25% dextrose + 1% lidocaine or procaine Guidance: Can be done freehand or under ultrasound guidance for precision Post-Injection Care Mild soreness or swelling is expected for 13 days Avoid anti-inflammatory medications (they may blunt the desired response) Gentle range of motion exercises encouraged Physical therapy may be added at any time Treatment Frequency Prolotherapy is typically performed every 34 weeks 36 sessions are usually recommended depending on severity and how you are progressing Clinical Evidence Supporting Prolotherapy for AC Joint Injury While large randomized controlled trials are limited for AC separation specifically, prolotherapy has demonstrated efficacy in multiple musculoskeletal conditions involving ligament and joint instability: Rabago et al
D.WangT.TamaeD.OgiJ.et al (2003)
THROUGH THE LENS You'll be seeing red, and that's the point
Staying well-hydrated, eating smaller meals, and gradually increasing your dose can help minimize these side effects
However, challenges persist in developing efficient approaches to controllably integrate antioxidant nanocatalysts with TRAF6 inhibitors into a single platform, as well as in achieving effective and targeted delivery of both agents to lesional macrophages to maximize their therapeutic potentials
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