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The SAM molecule is a universal methyl donor that is active in the methylation of many acceptor compounds, such as DNA, RNA, proteins, creatine, and phospholipid membranes

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(Aureli A, et al., International Journal of Molecular Sciences, 2023 PubMed: 38068911 ) B12 and lipid metabolism A review of pre-clinical and clinical evidence found low B12 is associated with adverse lipid profiles including elevated total cholesterol and LDL, particularly in people with type 2 diabetes

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To mitigate these effects, it's advisable to minimize the use of unnecessary medications as much as possible and seek out alternative treatment options that are less likely to disrupt gut health

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1 MNA: improves NAD+ / cellular health 2

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