Polymorphic depression of MTHFR activity (such as C677T) and folate/B12 insufficiency favor hyperhomocysteinemia and a low SAM:SAH ratio, both of which inhibit methyltransferases
B12 deficiency is one of the most treatable causes of cognitive and neurological decline, but only if you catch it before the damage becomes permanent
Enrichment of mitochondrial complex I proteins across AML-8 subtypes (n = 162 patients)
Key MeSH terms included: Food, Processed [Mesh], Mental Health [Mesh], Depressive Disorder [Mesh], Depression [Mesh], Sleep Deprivation [Mesh], Sleep Disorders, Circadian Rhythm [Mesh], Binge-Eating Disorder [Mesh], Anorexia Nervosa [Mesh], Bulimia Nervosa [Mesh], Food Addiction [Mesh], Autism Spectrum Disorder [Mesh], Attention Deficit Disorder with Hyperactivity [Mesh], Stress Disorders, Post-Traumatic [Mesh], Lipid Metabolism [Mesh], Lipid Metabolism Disorders [Mesh]
If you take a standard glutathione capsule, the digestive enzymes in your stomach and small intestine often break the molecule down into its individual amino acids before it ever reaches your bloodstream
Iron imperfection may also induce cognitive function defects and inadequate physical performance