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Incretin therapies mimic or enhance the action of gut hormones primarily glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) to increase glucose-dependent insulin secretion, suppress glucagon release, slow gastric emptying and reduce appetite, leading to improved glycaemic control and weight loss

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This proves our hypothesis about a new direction of T cell death in IAV infection

& Fromme, J

Aortic binding of AZD5248: mechanistic insight and reactivity assays to support lead optimization