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Postmenopausal considerations Postmenopausal women often experience reduced metabolism, higher fat mass, and increased risk of diabetes and heart disease

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PMID: 61 HuangDXuDChenWWuRWenYLiuAet al

However the down side to this increased mitochondrial function was that more oxidative damage occurred (3) , so the researchers decided to add the powerful mitochondrial antioxidant alpha lipoic acid (ALA) to the mix to see if they could get the best of both worlds: increased mitochondrial energy output, with reduced mitochondrial damage

however, the authors did not evaluate whether the antioxidative effect of VA was exerted exclusively through Nrf2 signaling (Wang et al