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Early responses include increases in vascular permeability and activation, together with the directed migration of leukocytes (neutrophils, monocytes and eosinophils) towards the site of injury, where the ground-work is being laid for the formation of a new extracellular matrix

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Therefore, future clinical trials on the effects of different curcumin formulations on depression are essential, to evaluate the potential difference in efficacy on depression

The primers used for the qRT-PCR experiment are listed in Additional file 1