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N/A not applicable, PBO placebo, y years a Status as of March 26, 2025 b Not listed for completed trials c Scalp, genitals, and/or palms of the hands and soles of the feet d Estimated enrollment In FRONTIER 1 and FRONTIER 2, there was no evidence of dose-related increases in AEs across the icotrokinra dosing groups

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Your Klinic provider will conduct a detailed evaluation to ascertain how suitable tirzepatide is for your situation