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Song Y, Liu J, Zhao K, Gao L, Zhao J

M., Brogden, R

Certain medications may interfere with tirzepatide's effectivenessparticularly drugs that affect gastric motility or glucose metabolism

Arnhem, The Netherlands: EAU Guidelines Office (2025)

Its not a question of six months or two months or anything like that

So many people in fact, that the drug supply in the UK faced severe shortages for months, as the medicine became practically unavailable for people with diabetes