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Research has examined its role in sleep regulation, stress modulation and neuroendocrine activity, including effects on circadian rhythm and interactions with the hypothalamic-pituitary axis

doi: 10.1093/jxb/erad324 109 ZermianiM.ZoninE.NonisA.BegheldoM.CeccatoL.VezzaroA.et al

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Therefore, on top of the benefits provided by macromolecular crowding, the supplementation with LOX/BMP1 has proved to further increase the capacity of the cells to deposit collagen onto an insoluble ECM