In VRK2-WT cells, as expected, most of SLC7A11 was redistributed to the ER after 1 h of BFA treatment, while at 4 h after BFA removal, almost all the cells showed co-localization of SLC7A11 and the Golgi marker Golgin-97
Overall, these findings suggested a link between patients with AHU or gout and disordered amino acid metabolism, which could provide a new direction for preventing acute attacks of gout
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