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The classical BRAT diet (bananas, rice, applesauce, toast) is the standard first-line approach for Zepbound diarrhea and any acute GI flare

[4] The proposed mechanism of action, based only on preclinical animal studies, involves potential modulation of growth factor pathways, particularly vascular endothelial growth factor (VEGF), which may promote angiogenesisthe formation of new blood vessels

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It is naturally produced in human gastric juice, but is also found in small amounts in the gastric juice of other mammals